The Antirachitic Action of Cod Liver Oil and Irradiated Ergosterol in Parathyroidectomized and Thymectomized Rats
نویسنده
چکیده
Cod liver oil and Viosterol in therapeutic doses are antirachitic in the absence of the parathyroid gland, or of the thymus, or of both.
منابع مشابه
The Resistance of the Antirachitic Substance in Cod Liver Oil to Reagents.*
The present communication records the first of a series of experiments begun at the suggestion of Professor E. V. McCollum on the chemical examination of antirachitic substances. The most familiar of these substances occurs in cod liver oil, and is commonly known as the antirachitic vitamin, or vitamin D. The cod liver oil which I used was an unfrozen, unadulterated oil, rendered at Bay Bulls, ...
متن کاملLxii. the Determination of Vitamin D
THE stability of preparations of vitamin D is of importance, both for the commercial products now on the market, and especially for the standard solutions which are widely used in estimations of the activity of other preparations. At present the International Standard adopted at the London Conference in 1931 consists of a solution of irradiated ergosterol in olive oil, and although this is like...
متن کاملThe Effect of Irradiated Ergosterol on Thyroparathyroidectomized
In a previous publication (1) it was shown that the feeding of cod liver oil to dogs for a period of 2 weeks before the removal of the thyroid and parathyroid glands greatly influenced the results of such an operation. The calcium of the blood serum fell as usual after parathyroidectomy, but the animals either did not develop tetany or the attacks were slight. The length of life of the treated ...
متن کاملThe determination of vitamin D: The relationship between graded doses of a standard solution of vitamin D, administered to young rats on a rachitogenic diet, and the ash content of their bones.
THE methods for the biological estimation of vitamin D, which are commonly used, are all based on a measurement of the calcification of the bones of rats, on a diet very low in phosphorus and high in calcium. The measurement of calcification is made either by X-ray photography of the epiphysis or growing end of a selected bone, or by staining the calcium deposited in it ("line" test), or by gra...
متن کاملCxix. Hypervitaminosis and Vitamin
THE object of this paper is to record a continuation of experiments in which the existence is demonstrated of a "balance" between the vitamin B complex on the one hand and vitamins A and D of cod-liver oil on the other. Only two previous communications bearing directly on this subject have appeared in the literature, so far as we are aware. In the first place, Hopkins [1923] mentioned that he h...
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ورودعنوان ژورنال:
- The Journal of Experimental Medicine
دوره 52 شماره
صفحات -
تاریخ انتشار 2003