Bovine thyroglobulin. 27 S iodoprotein interactions with thyroid membranes and formation of a 27 S iodoprotein in vitro.

نویسندگان

  • S Shifrin
  • E Consiglio
  • P Laccetti
  • G Salvatore
  • L D Kohn
چکیده

From the +Division of Cancer Biology and Diagnosis, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20205, §Section on Biochemistry of Cell Regulation, Laboratory of Biochemical Pharmacology, National Institute of Arthritis, Diabetes, and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20205, and 1Centro de Endocrinologia ed Oncologia Sperimentale del Consiglio Nazionale delle Ricerche, Naples, Italy

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Subunit structure of 27 S thyroid iodoprotein.

The dissociation of thyroid 27 S iodoprotein by sodium dodecyl sulfate (SDS) and by succinic anhydride was investigated by means of ultracentrifugation and polyacrylamide gel electrophoresis. The iodoprotein obtained from either a human or hog was dissociated into three kinds of subunits (S-19, S-17 and S-12) by SDS treatment. At increased concentrations of SDS, the S-12 subunit was predominant...

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عنوان ژورنال:
  • The Journal of biological chemistry

دوره 257 16  شماره 

صفحات  -

تاریخ انتشار 1982