An experimental study with a vaccine strain of porcine reproductive and respiratory syndrome virus to determine effects on viremia assessed by reverse transcriptase-polymerase chain reaction in pigs fed rations medicated with tilmicosin or non-medicated
نویسنده
چکیده
Materials and methods: Purebred Yorkshire pigs (N = 192) were each assigned to one of five treatment groups. Groups 1a and 1b remained PRRSV-negative (controls), while Groups 2, 3, and 4 were injected with a modified-live (MLV) PRRSV vaccine. Groups 1b and 2 were fed non-medicated feed. Rations contained tilmicosin at 400 mg per kg for Group 1a and Group 4 and 200 mg per kg for Group 3. Blood samples were collected to measure serum tilmicosin concentrations and assess PRRSV viremia. Bronchoalveolar lavage was performed and macrophages assessed for PRRSV viremia and tilmicosin concentrations.
منابع مشابه
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