Memory of chirality in cascade rearrangements of enediynes.
نویسندگان
چکیده
The cascade rearrangement of chiral enediynes 1c-e, involving successively 1,3-proton shift, Saito-Myers cyclization, 1,5-hydrogen atom transfer, and intramolecular coupling of the resulting biradical, proceeded at 80 °C to form tri- and tetracyclic heterocycles possessing a quaternary stereogenic center with a very high level of memory of chirality.
منابع مشابه
An efficient and recyclable hybrid nanocatalyst to promote enantioselective radical cascade rearrangements of enediynes.
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ورودعنوان ژورنال:
- Journal of the American Chemical Society
دوره 132 42 شماره
صفحات -
تاریخ انتشار 2010