Two new diterpenoid alkaloids, beiwusines A and B, from Aconitum kusnezoffii.
نویسندگان
چکیده
Two new atisine-type diterpenoid alkaloids, beiwusine A (1) and B (2), have been isolated from the roots of Aconitum kusnezoffii Reichb. Their structures were established on the basis of spectroscopic data. Beiwusines A and B are the first examples of atisine-type diterpenoid alkaloids having a hydroxyl group at C-1. In addition, one known diterpenoid alkaloid spiramine H (3) has been isolated.
منابع مشابه
Identification of diterpenoid alkaloids from the roots of Aconitum kusnezoffii Reihcb.
Three diterpenoid alkaloids, including an unreported compound, were isolated from the roots of Aconitum kusnezoffii Reichb. On the basis of spectral analysis, these three compounds were determined to be 1,15-dimethoxy-3-hydroxy-14-benzoyl-16-ketoneoline, benzoylaconine and aconitine.
متن کاملMesaconitine
The title compound, (1α,3α,6α,14α,15α,16β)-3,8,13,14,15-penta-hydr-oxy-1,6,16-trimeth-oxy-4-methoxy-methyl-20-methyl-acon-itan-8,14-diyl 8-acetate 14-benzoate, C(33)H(45)NO(11), a C(19) diterpenoid alkaloid, obtained from the roots of Aconitum kusnezoffii, has been crystallographically characterized in this study. Rings A, B and E have chair conformations, rings C and F display envelope conform...
متن کاملPharmacologically Active C-19 Diterpenoid Alkaloids from the Aerial parts of Aconitum laeve Royle
Two new lycoctonine type C19-diterpenoid alkaloids, swatinine-A (1), and swatinine-B (2), along with four known C19-diterpenoid alkaloids, foresticine (3), neoline (4), delvestine (5), and chasmanine (6), were isolated from the aerial parts of the Aconitum laeve Royle. The structures of compounds 1 and 2 were deduced on the basis of spectroscopic techniques (EI-MS, HREI-MS, H NMR, C NMR, HMQC, ...
متن کاملA comparative study on the traditional Indian Shodhana and Chinese processing methods for aconite roots by characterization and determination of the major components
BACKGROUND Aconitum is an indispensable entity of the traditional medicine therapy in Ayurveda and Traditional Chinese medicine (TCM), in spite of its known fatal toxicity characteristics. The prolonged use of this drug, irrespective of its known lethal effects, is governed by the practice of effective detoxification processes that have been used for decades. However, the processing methods of ...
متن کاملEffect of processing on the alkaloids in Aconitum tubers by HPLC-TOF/MS☆
According to the Chinese Pharmacopoeia 2015, only processed Aconitum tubers can be clinically applied, and the effect of processing is unclear. This research aimed to explore the effect of processing on cardiac efficacy of alkaloids in Aconitum tubers. First, the chemical ingredients in unprocessed and processed Aconitum tubers were identified and compared by using high performance liquid chrom...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Journal of Asian natural products research
دوره 1 2 شماره
صفحات -
تاریخ انتشار 1998