IL - 12 Generation of CD 8 T Cell Memory Is
نویسندگان
چکیده
منابع مشابه
Response Costimulation and Restoration by IL - 2 Differentiation by CD 80 / CD 86 - CD 28 T Cell + Control of Memory CD 8
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Serum parameters in the spectrum of coeliac disease: beyond standard antibody testing - a cohort study
BACKGROUND Invasive techniques are still required to distinguish between uncomplicated and complicated forms of CD. METHODS We set out to investigate the potential use of novel serum parameters, including IL-6, IL-8, IL-17, IL-22, sCD25, sCD27, granzyme-B, sMICA and sCTLA-4 in patients diagnosed with active CD, CD on a GFD, Refractory coeliac disease (RCD) type I and II, and enteropathy assoc...
متن کاملIL-12 priming during in vitro antigenic stimulation changes properties of CD8 T cells and increases generation of effector and memory cells.
Antigenic and costimulatory signals trigger a developmental program by which naive CD8 T cells differentiate into effector and memory cells. However, initial cytokine signals that regulate the generation of effector and memory CD8 T cells are not well understood. In this study, we show that IL-12 priming during in vitro antigenic stimulation results in the significant increase of both primary a...
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Background: Umbilical cord blood (UCB) is an alternative source of hematopoietic stem cell transplantation (HSCT), used in Leukemia treatment. CD26+ cells, a fraction of CD34 positive cells, are a major population of UCB cells which negatively regulate the in vivo homing and engraftment of HSCs. CD26 is highly expressed in various cells such as HSCs, immune cells, fibroblasts, and epithelial ce...
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