Enhancement of the diversity of polyoxins by a thymine-7-hydroxylase homolog outside the polyoxin biosynthesis gene cluster.
نویسندگان
چکیده
Polyoxins consist of 14 structurally variable components which differentiate at three branch sites of the carbon skeleton. Open reading frame (ORF) SAV_4805 of Streptomyces avermitilis, showing similarity to thymine-7-hydroxylase, was proved to enhance the diversity of polyoxins at the C-5 site of the 1-(5'-amino-5'-deoxy-β-d-allofuranuronosyl) pyrimidine moiety.
منابع مشابه
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ورودعنوان ژورنال:
- Applied and environmental microbiology
دوره 76 21 شماره
صفحات -
تاریخ انتشار 2010