Nanostructured lipid carriers (NLCs): A Novel based nano carrier for drug delivery and drug targeting

Aim: Nano structured lipid carriers (NLCs) contains solid and liquid lipids as the significant principle in the drug delivery system. This review is focused on various aspects involved in the preparation, structure, advantages, limitations, types, physiochemical characterization and wide pharmaceutical applications of SLN has been explored. Method:It is revealed that NLCs proved to be a promising drug delivery system over conventional carriers, including increase drug solubility, enhanced storage stability, developed permeability and bioavailability, decreased side effects, prolonged halflife and targeted delivery. Result:Solid lipid nanoparticles are emerging field of nanotechnology with more importance in drug delivery, clinical medicine and research. They are very significant to reach the goal of controlled and site specific drug delivery and therefore it has attracted many research people in this field. Conclusion: If this delivery system is properly designed and investigated it may open new vistas in therapeutics.