Production of epitope-specific antibodies using peptide-CpG-ODN-liposome complex without carriers and their application as a cancer vaccine in mice
نویسندگان
چکیده
Low efficacy of peptide vaccines limits their potential application. We developed a powerful strategy to produce epitope-specific antibodies using peptides. Immunization with novel formula into mice showed target-specific prophylactic and therapeutic effects against tumors. Our strategy will be useful for rapid eiptope screening, therapeutic antibody production and cancer vaccine development.
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