Quantitative Analysis of C - Reactive Protein (CRP) Using Quantum DOTs

نویسنده

  • Shahnila Raza
چکیده

In this study, a method of analyzing blood serum and quantification of C-reactive protein (CRP) using quantum dots is proposed. Blood serum is the one that contains many protein including CRP, and hence analyzing this could be helpful in diagnosing any disorder at the earliest. In this study, two experiments are done; one test on blood serum and the other on CRP. Initially, blood serum is separated from the blood and is taken in test tube is successively diluted using NaCl solution. These samples are illuminated using standard white light and the transmitted light is picked up from the color sensor (TCS2300). Similar kind of test is also performed on CRP samples at different concentration level. RGB values obtained from these two tests changes as the concentration of blood serum and CRP changes. Quantification of these colors would represent CRP concentration or concentration of protein content in the blood. Hence, by precisely calibrating these color changes against protein concentration would result in a device that could quantify blood chemical parameters.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Comparison of Two Methods: Qualitative and Quantitative Study of C - Reactive Protein

Abstract Background and Objective: C - reactive protein (CRP) is an acute phase protein produced in liver. It is less than 5 mg per deciliter in the serum and body fluids of normal individuals, but it is increased suddenly within a few hours following inflammatory reaction. In bacterial and viral infections, active rheumatic fever, acute myocardial infarction and rheumatoid arthritis are a...

متن کامل

Serum Adenosine Deaminase Activity and C-Reactive Protein Levels in Patients with Brucellosis

  Background and Objective: Brucellosis is a main transmittable zoonotic disease, which is endemic, and a common health burden in Iran. Adenosine deaminase (ADA) is an essential enzyme which is involved in purine metabolism and its role in immune system is very important. The aim of this study was to determine serum changes of ADA and C-reactive protein (CRP) levels in patients with brucellosi...

متن کامل

Rapid and quantitative detection of C-reactive protein based on quantum dots and immunofiltration assay

Convenient and rapid immunofiltration assays (IFAs) enable on-site "yes" or "no" determination of disease markers. However, traditional IFAs are commonly qualitative or semi-quantitative and are very limited for the efficient testing of samples in field diagnostics. Here, we overcome these limitations by developing a quantum dots (QDs)-based fluorescent IFA for the quantitative detection of C-r...

متن کامل

Rapid and quantitative detection of C-reactive protein using quantum dots and immunochromatographic test strips

BACKGROUND Rapid immunochromatographic tests can detect disease markers in 10-15 minutes, which facilitates clinical diagnosis and treatment programs. However, most immunochromatographic tests employ gold nanoparticles as reporters, and these have only moderate sensitivity and act as qualitative methods for analyzing high biomarker concentrations. METHODS In this study, we introduce quantum d...

متن کامل

Comparison of Homocysteine and C-reactive protein Levels Between Active and Inactive Veterans

Background: homocysteine and highly sensitive C-reactive protein (CRP) are two novel cardiovascular risk factors that induce atherosclerosis and myocardial infarction through inflammatory mechanisms. The aim of this study was to comparison of levels of these variables among athlete and nonathlete veterans. Methods: in this cross-sectional study two groups of athletes (N=8) and nonathlete (N=8) ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2016