hemocompatibility of carbon nanotubes

نویسندگان

  • Meixian Guo
  • Dejun Li
  • Mengli Zhao
  • Yiteng Zhang
  • Xiangyun Deng
  • Dongsheng Geng
  • Ruying Li
  • Xueliang Sun
  • Hanqing Gu
  • Rongxin Wan
چکیده

NH2 + implantation was performed on multiwalled carbon nanotubes (MWCNTs) prepared by chemical vapor deposition. The hemocompatibility of MWCNTs and NH2 -implanted MWCNTs was evaluated based on in vitro hemolysis, platelet adhesion, and kinetic-clotting tests. Compared with MWCNTs, NH2 -implanted MWCNTs displayed more perfect platelets and red blood cells in morphology, lower platelet adhesion rate, lower hemolytic rate, and longer kinetic blood-clotting time. NH2 -implanted MWCNTs with higher fluency of 1 × 10 ions/cm led to the best thromboresistance, hence desired hemocompatibility. Fourier transfer infrared and X-ray photoelectron spectroscopy analyses showed that NH2 + implantation caused the cleavage of some pendants and the formation of some new N-containing functional groups. These results were responsible for the enhanced hemocompatibility of NH2 -implanted MWCNTs.

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تاریخ انتشار 2013