Enteric bacterial toxins: mechanisms of action and linkage to intestinal secretion.
نویسندگان
چکیده
s of the 86th Annual Meeting of the American Society for Microbiology 1986. American Society for Microbiology, Washington, D.C. 496. Shapiro, M., J. Matthews, G. Hecht, C. Delp, and J. L. Madara. 1991.Stabilization of F-actin prevents cAMP-elicited Cl secretion in T84 cells.J. Clin. Invest. 87:1903–1909. 497. Shinagawa, K., S. Ueno, H. Konuma, N. Matsusaka, and S. Sugii. 1991. Purification and characterization of the vascular permeability factor pro-duced by Bacillus cereus. J. Vet. Med. Sci. 53:281–286. 498. Shinoda, S., H. Matsuoka, T. Tsuchie, S.-I. Miyoshi, S. Yamamoto, H. Taniguchi, and Y. Mizuguchi. 1991. Purification and characterization of alecithin-dependent haemolysin from Escherichia coli transformed by aVibrio parahaemolyticus gene. J. Gen. Microbiol. 137:2705–2711. 499. Shirai, H., H. Ito, T. Hirayama, Y. Nakamoto, N. Nakabayashi, K. Kumagai, Y. Takeda, and M. Nishibuchi. 1990. Molecular epidemiologic evidencefor association of thermostable direct hemolysin (TDH) and TDH-relatedhemolysin of Vibrio parahaemolyticus with gastroenteritis. Infect. Immun.
منابع مشابه
Induction of Apoptosis in Cultured Intestinal Epithelial Cells by Adhesin of Salmonella enterica serovar Typhimurium
Bacterial virulence mechanisms stem from the selective pressure of host environment and Salmonella enterica serovar Typhimurium (S. typhimurium) is an ideal example of this [1]. S. typhimurium causes self-limiting gastroenteritis and poses serious health problem in the regions of unhygienic conditions. Adhesin mediated attachment of enteric pathogens to host intestinal mucosa is an important ea...
متن کاملT6SS: The bacterial "fight club" in the host gut
The mammalian gut is home to a densely populated community of microorganisms that not only provide their host with nutritional benefits but also offer protection against foreign pathogens [1]. Since the gut is an environment limited in both space and nutrients, these microbes have evolved multiple mechanisms and strategies to either coexist or compete with other organisms that share the same re...
متن کاملSalmonella Typhimurium Type III Secretion Effectors Stimulate Innate Immune Responses in Cultured Epithelial Cells
Recognition of conserved bacterial products by innate immune receptors leads to inflammatory responses that control pathogen spread but that can also result in pathology. Intestinal epithelial cells are exposed to bacterial products and therefore must prevent signaling through innate immune receptors to avoid pathology. However, enteric pathogens are able to stimulate intestinal inflammation. W...
متن کاملBacterial Toxins and the Nervous System: Neurotoxins and Multipotential Toxins Interacting with Neuronal Cells
Toxins are potent molecules used by various bacteria to interact with a host organism. Some of them specifically act on neuronal cells (clostridial neurotoxins) leading to characteristics neurological affections. But many other toxins are multifunctional and recognize a wider range of cell types including neuronal cells. Various enterotoxins interact with the enteric nervous system, for example...
متن کاملEffect of vasoactive intestinal polypeptide (VIP) antagonism on rat jejunal fluid and electrolyte secretion induced by cholera and Escherichia coli enterotoxins.
BACKGROUND The enteric nervous system is important in the pathophysiology of intestinal fluid secretion induced by cholera toxin (CT), Escherichia coli heat labile (LT), and heat stable (STa) toxins. The neurotransmitters involved are not fully elucidated. Vasoactive intestinal polypeptide (VIP), a potent intestinal secretagogue present in the enteric nervous system, is increased after exposure...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Microbiological reviews
دوره 60 1 شماره
صفحات -
تاریخ انتشار 1996