1 2 3 Endocannabinoids mediate tachykinin induced effects in the lamprey locomotor 4 network
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چکیده
2 3 Endocannabinoids mediate tachykinin induced effects in the lamprey locomotor 4 network 5 6 7 8 9 10 11 Carolina Thörn Pérez, Russell H. Hill, Abdeljabbar El Manira, Sten Grillner 12 Nobel Institute for Neurophysiology 13 Department of Neuroscience, Karolinska Institutet, 14 SE17177 Stockholm, Sweden 15 16 Running head: Endocannabinoids mediate tachykinin effects 17 18 19 20 21 Corresponding author: S. Grillner, Dept. of Neuroscience, Karolinska Institute, 171 22 77 Stockholm, Sweden (E-mail: [email protected]). Fax: +46 8 349544 Tel: +46 8 23 52486900 24 ABSTRACT 25 Articles in PresS. J Neurophysiol (July 1, 2009). doi:10.1152/jn.00294.2009
منابع مشابه
Endocannabinoids mediate tachykinin-induced effects in the lamprey locomotor network.
The spinal network underlying locomotion in lamprey is composed of excitatory and inhibitory interneurons mediating fast ionotropic action. In addition, several modulator systems are activated as locomotion is initiated, including the tachykinin system and the metabotropic glutamate receptor 1 (mGluR1), the latter operating partially via the endocannabinoid system. The effects of mGluR1 agonist...
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2 All published papers were reproduced with permission from the publisher. ABSTRACT The metabotropic glutamate receptors, mGluRs, are G-protein coupled receptors. Eight subtypes have been cloned and divided into three groups depending on the amino acid sequence similarity, pharmacology and their signal pathways. In the lamprey spinal cord, group I mGluRs are located postsynaptically, while grou...
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