Anti-viral Effect of Herbal Medicine Korean Traditional Cynanchum Paniculatum (bge.) Kitag Extracts
نویسندگان
چکیده
BACKGROUND Pestiviruses in general, and Bovine Viral Diarrhea (BVD) in particular, present several potential targets for directed antiviral therapy. MATERIAL AND METHODS The antiviral effect of Cynanchum paniculatum (Bge.) Kitag (Dog strangling vine: DS) extract on the bovine viral diarrhea (BVD) virus was tested. First, a cytotoxicity test in MDBK (Madin-Darby bovine kidney) cells was done with all organic extract concentrations. RESULTS The cytotoxic concentration CC50 for the ethyl acetate (EA) extracts was 18.2 ug/ml. In the tissue culture, infectious dose (TCID50) assay, the BVD virus decreased when treated with 18.2 ug/ml of the ethyl acetate extracts. CONCLUSION Ethyl acetate extracts and fractions of the DS extract could be used as a potential antiviral for BVD.
منابع مشابه
C21 steroidal glycosides from the roots of Cynanchum paniculatum.
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