Temporal Disorientation Base Rates in Alzheimer’s Disease and Parkinson’s Disease

Base rates of impairment on the Temporal Orientation Scale (TOS; Benton et al.,) were reported for normal elderly (n=210) and patients with either Alzheimer’s disease (AD; n=112) or Parkinson’s disease (PD; n=189). The study hypothesis was that disorientation would be more frequent in ADs than in controls and PDs. Base rates for controls, PDs, and ADs were 1.00%, 22.22%, and 78.60% when disorientation was defined as ≥3 errors and 1.00%, 18.52%, and 72.30% when impairment was suggested by ≥4 errors. Receiver operating characteristic (ROC) analyses indicated excellent discrimination between controls and AD (AUC=0.919, 95% CI=0.879-0.958) along with good Sn and excellent Sp. Conversely, discrimination between control and PD groups was poor (AUC=0.642, 95% CI=0.5870.697) with low Sn and excellent specificity. *Corresponding author: David S. Kreiner, Dept. of Psychological Science, Lovinger 1111 University of Central Missouri Warrensburg, MO 64093-5089, USA, Tel: 660 5438076; E-mail: [email protected] Received April 17, 2015; Accepted June 15, 2015; Published June 18, 2015 Citation: Ryan JJ, Kreiner DS, Seeley JS, Paolo AM (2015) Temporal Disorientation Base Rates in Alzheimer’s Disease and Parkinson’s Disease J Gerontol Geriat Res 4: 221. doi:10.4172/2167-7182.1000221 Copyright: © 2015 Ryan JJ, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.