The structural and mechanochemical cycle of kinesin.
نویسندگان
چکیده
Kinesin is a microtubule-based motor protein that pulls vesicles or organelles towards the plus end of microtubules. Structural changes in the protein that drive motility are coupled to ATP binding and hydrolysis. Here, we attempt to integrate recent structural and kinetic results into a picture of the mechanochemical cycle of kinesin.
منابع مشابه
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ورودعنوان ژورنال:
- Trends in biochemical sciences
دوره 23 11 شماره
صفحات -
تاریخ انتشار 1998