Infantile orofacial hemangioma with ipsilateral peripapillary excavation in girls: a variant of the PHACE syndrome.

epithelium. A preexisting permeability defect may trigger the expression of celiac sprue by allowing ingested gluten to cross the epithelial barrier and incite a pathologic immune reaction in genetically susceptible individuals. Thus, one possible explanation for an association between IJFT and celiac sprue is an underlying systemic permeability defect that is responsible for both increased gluten hypersensitivity in the gut and endothelial decompensation in the retina. As more patients with celiac sprue are identified, future investigations should disclose whether there is a true causal association between celiac sprue and IJFT.