Polarity Is Destiny

نویسندگان

  • Liang Cai
  • Keith Mostov
چکیده

The GTPase Cdc42 specifies polarity in various biological processes. Kesavan et al. (2009) now demonstrate that Cdc42 also regulates epithelial cell polarity in the developing mouse pancreas, where it is required for tubule formation and maintenance. Furthermore, the polarization of epithelial tissue influences the differentiation of pancreatic progenitor cells, linking cell polarity to cell specification.

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عنوان ژورنال:
  • Cell

دوره 139  شماره 

صفحات  -

تاریخ انتشار 2009