Neutralizing and Complement-fixing Antibody Production and Resistance following Vaccination in Experimental Encephalitis Infections

Enduring Immunity following Vaccination of Mice with Formalin-inactivated Virus of Russian Spring-summer (far Eastern, Tick-borne) Encephalitis

A single course of two intraperitoneal injections of formalin-inactivated virus of Russian spring-summer encephalitis induced in albino mice a solidly immune state which endured almost throughout life. Active virus is therefore not essential for the production of a high degree of lasting immunity. The immune response to vaccination consists of resistance to peripherally introduced active virus ...

Neutralizing Antibody Response in Cattle Following Vaccination against Foot-and-Mouth Disease

Immunological Relationships among Central Nervous System Viruses

From observations carried out with the viruses of Russian spring-summer encephalitis, louping ill, W.E.E., and the Japanese B, St. Louis, and West Nile types of encephalitis, the following facts and inferences have been derived. 1. Russian encephalitis and louping ill viruses showed a close relationship by complement fixation, neutralization, and intraperitoneal cross-resistance tests. Intracer...

Diagnosis of California (La Crosse) encephalitis by precipitin techniques: a prospective study.

Counterelectrophoresis (CEP) and immunodiffusion (ID) were evaluated prospectively as methods for the early and rapid laboratory diagnosis of California encephalitis (CE). CEP and ID studies were done on paired sera from 127 patients with acute central nervous system infections. After the precipitin tests were completed, conventional hemagglutination-inhibition, neutralizing, and complement fix...

Neutralizing antibody responses to varicella-zoster virus.

Neutralization of varicella-zoster (V-Z) virus by human sera and immune rhesus monkey sera was enhanced by fresh guinea pig complement. There was no marked difference in the degree to which complement enhanced neutralization by sera from current V-Z virus infections and sera from long-past varicella infections. Immunoglobulin G neutralizing antibody in sera from varicella cases was enhanced by ...