Engineering Vascularized Human Adipose Tissue
نویسندگان
چکیده
Introduction Due to complications of currently available therapies, the clinical impetus to engineer adipose tissue for the correction of soft tissue defects is high. Unfortunately, poor survival of in vitro-engineered adipose tissue after transplantation is still a major hurdle for clinical use. The main reason for this poor survival is postulated to be insufficient vascularization. In this study, we aim to improve the in vivovascularization of engineered adipose tissue by pre-forming vascular structures within in vitroengineered adipose tissue constructs that can integrate with the host vascular system upon transplantation.
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