Comparative studies on oestrogen-induced rat uterus peroxidase and rat eosinophil peroxidase.
نویسندگان
چکیده
Rat eosinophil peroxidase and rat uterine peroxidase II showed similar electrophoretic mobilities, molecular weights, specific activities and spectral properties and could be purified by essentially identical techniques. Antibodies raised against the uterine enzyme strongly inhibited the eosinophil enzyme. It is suggested that rat eosinophil peroxidase and rat uterine peroxidase II may well be one and the same enzyme.
منابع مشابه
Uterine type II estrogen-binding sites are not of eosinophil origin.
A recent report by Lyttle et al. (Lyttle, C. R., Medlock, R. L., and Sheehan, D. M. (1984) J. Biol. Chem. 259, 2697-2700) suggested that nuclear type II sites in the rat uterus are of eosinophil origin and may represent [3H]estradiol binding to eosinophil peroxidase. To further evaluate this hypothesis we examined the response of nuclear type II sites to estrogen under conditions where eosinoph...
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ورودعنوان ژورنال:
- The Biochemical journal
دوره 207 3 شماره
صفحات -
تاریخ انتشار 1982