Longevity, lipids and C. elegans
نویسنده
چکیده
Scientific investigation of mechanisms that determine lifespan can be divided into three general approaches. The first approach (the comparative method) began over a century ago comparing species differing greatly in maximum longevity and implicated a role for the speed of metabolism in determining the length of life [1]. The second approach commenced after the 1930s investigated the mechanisms whereby “calorierestriction” extended lifespan [2]. The third approach gained popularity in the 1990s and centred on genetic mutations that significantly extend longevity [3]. There has been little overlap between these three approaches. The paper by Shmookler Reis et al. in this issue [4] is significant in that it advances our understanding by combining the genetic mutants approach with recent insights from the first approach. Disciplines Medicine and Health Sciences | Social and Behavioral Sciences Publication Details Hulbert, A. J. (2011). Longevity, lipids and C. elegans. Aging, 3 (2), 81-82. This journal article is available at Research Online: http://ro.uow.edu.au/smhpapers/1611
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