ALLEN Developing Mouse Brain Atlas

The Allen Developing Mouse Brain Atlas provides in situ hybridization (ISH) data for ~2,000 genes over embryonic and postnatal timepoints, and many of these genes display very restricted spatial expression patterns that change over time. Events that shape the development of the brain from an undifferentiated set of precursors to a mature, functioning organ occur at different times in different regions, and thus the ability to localize gene expression at specific stages of development is highly desirable. The informatics data processing pipeline developed by the Allen Institute enables the navigation and analysis of this large and complex dataset to identify gene expression with precise spatial and temporal regulation.