“Nerve Hyper-Sensitivity” Syndromes
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Comparison of pain behavior responses in two peripheral neuropathic models (SNI, CCI) in rat
Introduction: Peripheral nerve injury leads to neuropathic pain syndromes and different sensation like allodynia and hyperalgesia. Different animal models of neuropathic pain are used to study the neuropathic pain mechanisms. The present study was performed on two models, (SNI). The purpose of this study was comparing the behavioral responses of yhese two models and the role of saphenous and...
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Neuropathic pain accompanies peripheral nerve injury after a wide variety of insults including metabolic disorders, traumatic nerve injury, and neurotoxic drugs. Chemotherapy-induced neuropathic pain, caused by drugs such as vincristine and taxol, occurs in cancer patients who receive these drugs as antineoplastic agents. Although a variety of remediations have been attempted, the absence of kn...
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