Engraftment Syndrome (es)
نویسندگان
چکیده
Engraftment syndrome (ES) is an early complication of hematopoietic stem cell transplantation (HSCT) that occurs around neutrophil engraftment time and is attributed to the sudden cytokine discharge associated with robust engraftment of transplanted cells. The secreted cytokines cause a clinical picture suggestive of an exaggerated inflammatory response. This complication has been described both in autologous and allogeneic transplantation.
منابع مشابه
Pre-engraftment syndrome: clinical significance and pathophysiology
In 2003, the Takaue group observed clinical features such as fever, skin rash and fluid retention that mimicked engraftment syndrome (ES) in cord blood transplantation (CBT) patients who received reduced-intensity conditioning regimens, and referred to this event as an "early inflammatory syndrome (EIS)" (personal communication). Around the same time, we also observed these manifestations in pa...
متن کاملEngraftment syndrome in hematopoietic stem cell transplantations.
Hematopoietic stem cell transplantation (HSCT) is an increasingly common treatment option for malignant and nonmalignant diseases, but it has significant associated morbidity and mortality. Nurses caring for HSCT recipients must be aware of all potential complications, including engraftment syndrome (ES). Previous nursing literature has included little information on this syndrome, which often ...
متن کاملEngraftment of engineered ES cell–derived cardiomyocytes but not BM cells restores contractile function to the infarcted myocardium
Cellular cardiomyoplasty is an attractive option for the treatment of severe heart failure. It is, however, still unclear and controversial which is the most promising cell source. Therefore, we investigated and examined the fate and functional impact of bone marrow (BM) cells and embryonic stem cell (ES cell)-derived cardiomyocytes after transplantation into the infarcted mouse heart. This pro...
متن کاملEngraftment of embryonic stem cell-derived hematopoietic progenitor cells is regulated by natural killer cells
Embryonic stem (ES) cells possess the remarkable ability to form cells and tissues from all three germ layers, a characteristic known as pluripotency. In particular, the generation of ES cell‐derived hematopoietic cells could serve as an alternate source of hematopoietic stem cells for transplantation in place of bone marrow cells, which are limited by donor availability and high immunogenicit...
متن کاملCase of engraftment syndrome appearing as scratch dermatitis
Dear Editor, Scratch dermatitis, or flagellate erythema, is characterized by linear erythematous/hyperpigmented streaks, and can be caused by shiitake mushroom, bleomycin, dermatomyositis and Still’s disease. Engraftment syndrome (ES) presents with pyrexia, maculopapular eruption and edema during neutrophil recovery following hematopoietic stem cell transplantation. Here, we describe a case wit...
متن کامل