Platinum coil coatings to increase thrombogenicity: a preliminary study in rabbits.
نویسندگان
چکیده
The authors investigate a modification of the Gugliemi detachable coil. They have developed a rabbit model and coating technique to test differences in thrombogenicity of platinum coils with a variety of polyurethanes.
منابع مشابه
Endovascular histologic effects of ultrathin gold- or vitronectin-coated platinum aneurysm coils in a rodent arterial occlusion model: a preliminary investigation.
BACKGROUND AND PURPOSE Novel stratagems to improve the efficacy of platinum coils in occluding cerebral aneurysms have primarily involved coating coils with materials thought likely to provoke more desirable histologic reactions. No investigations to date, however, have evaluated the utility of gold or vitronectin coatings, despite known endovascular histologic effects of these agents, which ma...
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1. Kallmes DF, Fujiwara NH, Yuen D, et al. A collagen-based coil for embolization of saccular aneurysms in a New Zealand White rabbit model. AJNR Am J Neuroradiol 2003;24:591–96 2. Dawson RC 3rd, Shengelaia GG, Krisht AF, et al. Histologic effects of collagenfilled interlocking detachable coils in the ablation of experimental aneurysms in swine. AJNR Am J Neuroradiol 1996;17:853–58 3. Murayama ...
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BACKGROUND Stent thrombosis is a lethal complication of endovascular intervention. Concern has been raised about the inherent risk associated with specific stent designs and drug-eluting coatings, yet clinical and animal support is equivocal. METHODS AND RESULTS We examined whether drug-eluting coatings are inherently thrombogenic and if the response to these materials was determined to a gre...
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ورودعنوان ژورنال:
- AJNR. American journal of neuroradiology
دوره 14 4 شماره
صفحات -
تاریخ انتشار 1993