Lyme arthritis outcomes in children: a single center cohort study
نویسندگان
چکیده
Methods Children evaluated in the pediatric rheumatology clinics of Penn State Children’s Hospital and diagnosed with Lyme arthritis between 2002 and 2010 were reviewed from initial contact to the most recent follow-up documentation available. The diagnosis of Lyme arthritis in all cases was based on the presentation of synovitis and/ or enthesitis in combination with positive Western blot assays by CDC criteria. Children with transient arthritis (< 3 mo duration) were compared with children manifesting chronic arthritis (>3 mo) by presenting laboratory features and clinical features throughout their follow-up.
منابع مشابه
Children with Lyme Arthritis in Slovenia: Demographic, Clinical and Laboratory Characteristics
Introduction: Lyme borreliosis is an infectious disease caused by B. burgdorferi sensu lato and transmitted by a tick. In Slovenia it is highly endemic and common in children. A clinical sign of early disseminated and late disease is Lyme arthritis (LA). The aim of the study was to define demographic, clinical and laboratory characteristics of children with Lyme arthritis. Methods: The retrospe...
متن کاملDiagnostic impact of routine Lyme serology in recent-onset arthritis: results from the ESPOIR cohort.
OBJECTIVES Lyme disease may be considered by rheumatologists in patients with recent-onset arthritis, even in the absence of suggestive symptoms. The aim of this study was to determine the diagnostic impact of routine Lyme serology in a French cohort of patients with recent-onset arthritis affecting at least 2 joints. METHODS We performed an ancillary study of a French prospective multicentre...
متن کاملLong-term outcomes of persons with Lyme disease.
CONTEXT Few data exist about the long-term outcomes of patients with Lyme disease. OBJECTIVE To assess the long-term outcomes of patients with Lyme disease. DESIGN Two-part project including a community-based longitudinal cohort study and a matched cohort study. SETTING AND PARTICIPANTS Six hundred seventy-eight patients identified from a random sample of all reports of Connecticut reside...
متن کاملAssociation of a Toll-like receptor 1 polymorphism with heightened Th1 inflammatory responses and antibiotic-refractory Lyme arthritis.
OBJECTIVE Single-nucleotide polymorphisms (SNPs) that alter immune function, inflammatory responses, and disease susceptibility have been identified in several genes encoding Toll-like receptors (TLRs). The TLR SNPs with the best evidence of an effect on immune function are those in TLR1 (1805GG), TLR2 (2258GA), and TLR5 (1174CT). This study was undertaken to assess the frequency and functional...
متن کاملRole of psychiatric comorbidity in chronic Lyme disease.
OBJECTIVE To evaluate the prevalence and role of psychiatric comorbidity and other psychological factors in patients with chronic Lyme disease (CLD). METHODS We assessed 159 patients drawn from a cohort of 240 patients evaluated at an academic Lyme disease referral center. Patients were screened for common axis I psychiatric disorders (e.g., depressive and anxiety disorders); structured clini...
متن کامل