Linking existing in vitro dermal absorption data to physicochemical properties : contribution to the 1 design of a weight - of - evidence approach for the safety evaluation of cosmetic ingredients with low 2 dermal bioavailability 3
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Dermal toxicity of Colloidal Nanosilver in Albino Rabbit: A New Approach to Physicochemical Properties
Objective(s): Silver nanoparticles have been widely used as new potent antimicrobial agents in cosmetic and hygienic products, as well as in new medical devices. Serious concerns have been expressed on the potential health risks of dermal applications of nanosilver containing consumer products (AgNPs), therefore regulatory health risk assessment has become necessary for the saf...
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In this study, tretinoin microemulsion has been formulated based on phase diagram studies by changing the amounts and proportions of inactive ingredients, such as surfactants, co-surfactants and oils. The effects of these variables have been determined on microemulsion formation, particle size of the dispersed phase and release profile of tretinoin from microemulsion through dialysis membrane. ...
متن کاملFormulation and In-vitro Evaluation of Tretinoin Microemulsion as a Potential Carrier for Dermal Drug Delivery
In this study, tretinoin microemulsion has been formulated based on phase diagram studies by changing the amounts and proportions of inactive ingredients, such as surfactants, co-surfactants and oils. The effects of these variables have been determined on microemulsion formation, particle size of the dispersed phase and release profile of tretinoin from microemulsion through dialysis membrane. ...
متن کاملZinc Oxide Nanoparticles in Cosmetic Products
This study is focused on the evaluation of zinc oxide properties and behavior at commercially available cosmetic ingredients by in vitro methods of dermal absorption of zinc oxide and its subsequent chemical determinations. Two methods for determination of ZnO were used and the results were compared. The spectrophotometric method (SPM) was selected for its sensitivity and atomic absorption spec...
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Background: There is unprecedented increase in the processing and packaging of many plant materials into food supplements, herbal medicine, skincare and cosmetic products for human needs. Baphia nitida is used for topical skincare products. Toluene, a toxic aromatic solvent, is increasingly being used in the production of these skincare and cosmetic products in many industries. This study ass...
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