Comment on "Brain IRS2 signaling coordinates life span and nutrient homeostasis".
نویسندگان
چکیده
Taguchi et al. (Reports, 20 July 2007, p. 369) reported that mice heterozygous for a null mutation in insulin receptor substrate-2 (Irs2) display a 17% increase in median life span. However, using the same mouse model, we find no evidence for life-span extension and suggest that the findings of Taguchi et al. were due to atypical life-span profiles in their study animals.
منابع مشابه
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http://www.sciencemag.org/cgi/content/full/317/5836/369 version of this article at: including high-resolution figures, can be found in the online Updated information and services, http://www.sciencemag.org/cgi/content/full/317/5836/369/DC1 can be found at: Supporting Online Material found at: can be related to this article A list of selected additional articles on the Science Web sites http://w...
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ورودعنوان ژورنال:
- Science
دوره 320 5879 شماره
صفحات -
تاریخ انتشار 2007