9-[4-Hydroxy-3-(hydroxymethyl)butyl]guanine monohydrate
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چکیده
In the mol-ecular structure of the title compound, also named penciclovir monohydrate, C(10)H(15)N(5)O(3)·H(2)O, the 4-hydr-oxy-3-hydroxy-methyl-but-1-yl group is connected to guanine through an N atom of the imidazole ring. Water mol-ecules stabilize the mol-ecular packing by forming O-H⋯O hydrogen bonds. A three-dimensional network is generated via inter-molecular N-H⋯N, N-H⋯O, O-H⋯N and O-H⋯O hydrogen bonding.
منابع مشابه
5-{(2S,3R,4S,5S,6R)-3,4-Dihydroxy-6-hydroxymethyl-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydropyran-2-yloxy]tetrahydropyran-2-yloxy}-7-hydroxy-2-(4-hydroxyphenyl)chromen-4-one monohydrate
In the title compound, C(27)H(30)O(14)·H(2)O, the hydroxy-phenyl ring makes a dihedral angle of 20.05 (11)° with the chromenone ring system. The crystal structure is stabilized by intra- and inter-molecular O-H⋯O hydrogen bonds. The absolute configuration was assigned on the basis of an analagous structure.
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The deprotonated Schiff base ligand in the title compound, [Sn(C(4)H(9))(2)(C(18)H(12)N(2)O(3))], O,N,O'-chelates to the Sn atom, which is five-coordinated in a cis-C(2)NO(2)Sn trigonal-bipyramidal environment. The apical sites are occupied by the O atoms [O-Sn-O = 155.2 (2)°]. The hydr-oxy group is a hydrogen-bond donor to the two-coordinate N atom of an adjacent mol-ecule, the hydrogen-bondin...
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In the title compound, C(9)H(20)NO(+)·HO(4)S(-)·H(2)O, the piperi-dinium ring adopts a chair conformation. Inter-molecular O-H⋯O and N-H⋯O hydrogen bonds form an extensive three-dimensional network, which consolidates the crystal structure.
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