Intravesical instillation of cidofovir in the treatment of hemorrhagic cystitis caused by adenovirus type 11 in a bone marrow transplant recipient.
نویسندگان
چکیده
Hemorrhagic cystitis that occurs late after bone marrow transplantation (BMT) in BMT recipients is often associated with adenovirus or polyomavirus BK infections. Intravesical instillation of cidofovir in a BMT recipient with intractable hemorrhagic cystitis resulted in clinical improvement. Local cidofovir therapy for viral hemorrhagic cystitis could be an alternative to intravenous administration of cidofovir.
منابع مشابه
Prostaglandin E2 bladder instillation for the treatment of hemorrhagic cystitis after allogeneic bone marrow transplantation.
BACKGROUND Hemorrhagic cystitis (HC) is a major complication of high-dose cyclophosphamide therapy used in the preparative regimen for allogeneic or autologous bone marrow transplantation. Several viruses (adenovirus, cytomegalovirus and polyomavirus BK) have also been implicated in the etiology of HC. No one established method of treatment is as yet available. MATERIALS AND METHODS HC develo...
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متن کاملSuccessful treatment of hemorrhagic cystitis secondary to cyclophosphamide chemotherapy with intravesical instillation of prostaglandin F2 alpha.
The treatment of cyclophosphamide-induced hemorrhagic cystitis is difficult. We report a successful case of severe cyclophosphamide-induced hemorrhagic cystitis treated with intravesical instillation of prostaglandin F2 alpha. A 32-year-old woman underwent high-dose cyclophosphamide conditioning before the autologous bone marrow transplantation. She developed clot retention which required conti...
متن کاملBK Polyomavirus Hemorrhagic Cystitis following Allogeneic Bone Marrow Transplant with Haploidentical Related Donor: Case Reports from Two Patients
Hemorrhagic cystitis is a common complication in allogeneic bone marrow transplant recipients [1]. The association of BK virus cystitis and allogeneic bone marrow transplant was first described two decades ago [2]. The incidence of hemorrhagic cystitis in allogeneic bone marrow transplant patients is reported up to 70%, while BK viruria after allogeneic bone marrow transplant is detected in 50 ...
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عنوان ژورنال:
- Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
دوره 40 1 شماره
صفحات -
تاریخ انتشار 2005