Nephrotic syndrome in adult Africans in Nairobi.

نویسندگان

  • R D Barr
  • P H Rees
  • P E Cordy
  • A Kungu
  • B A Woodger
  • H M Cameron
چکیده

The adult nephrotic syndrome as met with in Nairobi is predominantly encountered in young sophisticated African women, most of whom began to use skin-lightening creams containing mercury before the symptomatic onset of their illness. The particular form of mercury involved is well known to cause the nephrotic syndrome in other circumstances-for example, when applied to the skin in the treatment of psoriasis. In these circumstances the pathogenetic mechanism is thought to be of an idiosyncratic type. The use of mercury-containing skin-lightening creams in the patients studied seemed to be particularly associated with a "minimal-change" ("light-negative") renal glomerular lesion, this lesion being present in half of the patients. The prognosis in this group of patients seems remarkably good, with 50% entering remission, 77% of these doing so spontaneously on discontinuing the use of the creams.

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عنوان ژورنال:
  • British medical journal

دوره 2 5806  شماره 

صفحات  -

تاریخ انتشار 1972