Reconstructing spatial transport distributions in the nuclear pore complex from 2D images—how reliable is it?
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چکیده
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منابع مشابه
Structure and gating of the nuclear pore complex
Nuclear pore complexes (NPCs) perforate the nuclear envelope and allow the exchange of macromolecules between the nucleus and the cytoplasm. To acquire a deeper understanding of this transport mechanism, we analyse the structure of the NPC scaffold and permeability barrier, by reconstructing the Xenopus laevis oocyte NPC from native nuclear envelopes up to 20 Å resolution by cryo-electron tomog...
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