Ir-catalysed formation of C-F bonds. From allylic alcohols to α-fluoroketones.
نویسندگان
چکیده
A novel iridium-catalysed tandem isomerisation/C-F bond formation from allylic alcohols and Selectfluor® to prepare α-fluorinated ketones as single constitutional isomers is reported.
منابع مشابه
Allylic alcohols as synthetic enolate equivalents: isomerisation and tandem reactions catalysed by transition metal complexes.
Allylic alcohols can be isomerised into carbonyl compounds by transition metal complexes. In the last few years, catalyst design and development have resulted in highly efficient isomerisations under mild reaction conditions, including enantioselective versions. In addition, the isomerisation of allylic alcohols has been combined with C-C bond forming reactions when electrophiles such as aldehy...
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ورودعنوان ژورنال:
- Chemical communications
دوره 47 29 شماره
صفحات -
تاریخ انتشار 2011