Survival in Alzheimer disease

نویسندگان

  • E. P. Helzner
  • N. Scarmeas
  • S. Cosentino
  • M. X. Tang
  • N. Schupf
  • Y. Stern
چکیده

Methods: AD cases were identified in the Washington Heights Inwood Columbia Aging Project, a longitudinal, community-based study of cognitive aging in Northern Manhattan. The sample comprised 323 participants whowere initially dementia-free but developed AD during study follow-up (incident cases). Participants were followed for an average of 4.1 (up to 12.6) years. Possible factors associated with shorter lifespan were assessed using Cox proportional hazards models with attained age as the time to event (time from birth to death or last follow-up). In subanalyses, median postdiagnosis survival durations were estimated using postdiagnosis study follow-up as the timescale.

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تاریخ انتشار 2008