Compounding, Stability and Beyond-use Dates
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چکیده
INTRODUCTION Considerations in the extemporaneous compounding of prescriptions include stability and “beyond-use” dating. It should be noted that "Expiration Dates" are placed on commercially manufactured products and "Beyond-Use Dates" are used for compounded preparations. Prescriptions requiring extemporaneous compounding by the pharmacist generally do not require the extended shelf-life that commercially manufactured and distributed products do because they are intended to be utilized soon after receipt by the patient and are used only during the immediate course of the prescribed treatment. However, these compounded prescriptions must remain stable and efficacious during the course of their use and the compounding pharmacist must employ formulative components and techniques which will result in a stable product.
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