“Point” Centromeres of Saccharomyces Harbor Single Centromere-Specific Nucleosomes
نویسندگان
چکیده
The "point" centromere of budding yeast is genetically defined by an ≈ 125-bp sequence. Recent fluorescence measurements of kinetochore clusters have suggested that this sequence specifies multiple centromere histone 3 (CenH3) nucleosomes. However, high-resolution mapping demonstrates that there is only one CenH3 nucleosome per centromere, providing biochemical confirmation of the point centromere model.
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عنوان ژورنال:
دوره 190 شماره
صفحات -
تاریخ انتشار 2012