Spontaneous rupture of spleen during periferal blood stem cell mobilization in a patient with breast cancer.
نویسندگان
چکیده
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منابع مشابه
Spleen enlargement following recombinant human granulocyte colony-stimulating factor administration for peripheral blood stem cell mobilization.
BACKGROUND AND OBJECTIVES Recombinant human granulocyte colony-stimulating factor (rhG-CSF) is widely used to mobilize peripheral blood stem cells (PBSC) for autologous or allogeneic transplants. Such treatment may cause spleen enlargement; exceptionally, spontaneous spleen rupture has been reported. We investigated changes in spleen size during stem cell mobilization. DESIGN AND METHODS We e...
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Background: Adipose derived stem cells (ASCs) provoke the accumulation and expansion of regulatory T cells, leading to the modulation of immune responses in tumor microenvironment. Objective: To assess the effect of tumoral ASCs on the trend of regulatory T cells differentiation. Methods: Peripheral blood naïve CD4+ T cells were co-cultured with ASCs derived from breast cancer or normal breast ...
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Hematopoietic stem cells (HSCs), which have the ability to differentiate into various types of blood cell lines, are usually separate from the bone marrow. But these cells are also present in a small amount in the peripheral blood, and their amounts increase in blood following injection of G-CSF. However, the mechanism involved in moving HSCs under the influence of G-CSF is unknown. The aim of ...
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Background Cancer stem cells play crucial roles in resistance to therapeutic schemes and relapse of disease, so it is important to find targeted therapies that kill them selectively. Breast cancer is the most common cancer in females living in all part of the world including Iran and it has an important burden in public health with direct impact on patients’ families. Breast cancer in young ad...
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ورودعنوان ژورنال:
- Haematologica
دوره 85 5 شماره
صفحات -
تاریخ انتشار 2000