Controlled Assembly of Magnetic Biomolecular Nanostructures
نویسندگان
چکیده
Two optimized strategies were successfully established to develop biomolecule-based magnetic nanoassemblies. Streptavidin-coated and amine-coated magnetic nanoparticles were chosen as model scaffolds onto which double-stranded DNA and human immunoglobulin G were specifically conjugated in succession, using biotin-streptavidin interaction or covalent cross-linkers. The success of this study opens the prospect of developing selective and sensitive nanoparticle-based structures for diagnostics or drug delivery. Keywords—Antibody, DNA, linker, magnetic nanoparticles, streptavidin
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