Adding aspirin to antipsychotics reduces psychopathology in adults with schizophrenia spectrum disorders.

نویسندگان

  • Valeria Mondelli
  • Carmine M Pariante
چکیده

ED FROM Laan W, Grobbee DE, Selten JP, et al. Adjuvant aspirin therapy reduces symptoms of schizophrenia spectrum disorders: results from a randomized, double-blind, placebocontrolled trial. J Clin Psychiatry 2010;71:520–7. Correspondence to: Wijnand Laan, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, PO box 85500, 3508 GA, Utrecht, The Netherlands; w.laan@umculrecht Source of funding: The Stanley Medical Research Institute.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Comparing the Effects of Adjunct Aspirin and Simvastatin on Psychopathology among Inpatients with Schizophrenia

Objectives: As a severe mental health condition, schizophrenia presents a chronic and complex clinical manifestation and neuropathology. A large body of literature exists on the pharmacological treatment of schizophrenia. However, evidence on some dimensions of such interventions (e.g., eligible candidates, potential predicting factors of the therapeutic outcomes, safe implementation of these i...

متن کامل

Adjuvant aspirin therapy reduces symptoms of schizophrenia spectrum disorders: results from a randomized, double-blind, placebo-controlled trial.

OBJECTIVE Inflammatory processes may play a role in the pathophysiology of schizophrenia. The aim of this study was to determine the efficacy of adjuvant treatment with aspirin (acetylsalicylic acid) in schizophrenia spectrum disorders. METHOD This randomized, double-blind, placebo-controlled study was conducted between May 2004 and August 2007. Seventy antipsychotic-treated inpatients and ou...

متن کامل

اختلالات روان‌پزشکی و بدکارکردی‌های جنسی

Sexual dysfunctions are highly prevalent among patients with psychiatric disorders. These dysfunctions may be caused by the psychopathology and pharmacotherapy of the psychiatric disorders. A lot of researches have studied the relationship between sexual dysfunctions and psychiatric disorders. The results of the researches show that psychiatric disorders have an important role in the developmen...

متن کامل

Evaluation of the efficacy and safety of pregabalin as an adjuvant to antipsychotics in patients with chronic schizophrenia: a six-week pilot double-blind placebo-controlled trial

Introduction and objectives: Antipsychotics or dopamine receptor antagonists are the major components of treatment but about 10-20% of patients with schizophrenia do not benefit from treatment with antidopaminergic agents, indicating other neuronal systems may be involved in this disorder (2). Dysregulation of both excitatory and inhibitory mechanisms N-Methyl-D-aspartic acid (NMDA) and γ-Amino...

متن کامل

Neurological soft signs and their relationship to cognitive and clinical efficacy of atypical antipsychotics in schizophrenia.

Neurological soft signs (NSS) are nonspecific indicators of brain dysfunction that are found to be in excess and correlated with cognitive dysfunction and psychopathology in patients with schizophrenia. The aim of the study was to examine whether the severity of NSS determines the efficacy of atypical antipsychotics in schizophrenia. Forty-three patients with schizophrenia were assessed on psyc...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Evidence-based mental health

دوره 13 4  شماره 

صفحات  -

تاریخ انتشار 2010