Abstract: Occupational Exposure to Organophos- phate and Carbamate Pesticides Affects Sperm Chromatin Integrity and Reproductive Hormone Levels among Venezuelan Farm Workers: Leticia

نویسندگان

  • Leticia Miranda-Contreras
  • Roald Gómez-Pérez
  • Gerardo Rojas
  • Ibis Cruz
  • Lisbeth Berrueta
  • Siham Salmen
  • Melisa Colmenares
  • Silvio Barreto
  • Alirio Balza
  • Leisalba Zavala
  • Yasmin Morales
  • Yuri Molina
  • Lenin Valeri
  • Carlos A. Contreras
  • Jesús A. Osuna
چکیده

and BuChE inhibition. Significant increments were observed in sperm DFI with significant decreases in some semen parameters. DFI was negatively correlated with BuChE, sperm concentration, morphology and vitality in these workers. The levels of Tt, PRL, FT4 and TSH appeared to be normal; however, there was a tendency for increased LH and FSH levels in exposed workers. Conclusions: Our results confirm the potential impact of chronic occupational exposure to OP/CB pesticides on male reproductive function, which may cause damage to sperm chromatin, decrease semen quality and produce alterations in reproductive hormones, leading to adverse reproductive health outcomes. (J Occup Health 2013; 55: 195−203)

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تاریخ انتشار 2013