[Activation-induced polarized recycling targets T cell receptors to the immunological synapse].
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منابع مشابه
Coordination of T cell activation and migration through formation of the immunological synapse.
T cell activation is based on interactions of T cell antigen receptors with MHC-peptide complexes in a specialized cell-cell junction between the T cell and antigen-presenting cell-the immunological synapse. The immunological synapse coordinates naïve T cell activation and migration by stopping T cell migration with antigen-presenting cells bearing appropriate major histocompatibility complex (...
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DCs activate NK cells during innate immune responses to viral infections. However, the composition and kinetics of the immunological synapse mediating this interaction are largely unknown. Here, we report the rapid formation of an immunological synapse between human resting NK cells and mature DCs. Although inhibitory NK cell receptors were polarized to this synapse, where they are known to pro...
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ورودعنوان ژورنال:
- Medecine sciences : M/S
دوره 21 1 شماره
صفحات -
تاریخ انتشار 2005