The Etiology of Hyperostosis
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چکیده
Hyperostosis cranii or metabolic craniopathy was first recognised as an essential part of Morgagni’s syndrome of virilism, obesity and hyperostosis frontalis. It is a syndrome of uncertain origin which was believed to occur almost exclusively in middle aged and elderly women. More recently it has been shown to occur in younger women and rarely to occur in men. The syndrome is characterised by thickening of the inner table of the skull, more usually in the frontal region, but it may also occur over other parts of the skull, including the basal bones and the orbital plate. There may be generalised thickening of the whole calvarium. In the frontal region especially, the inner surface of the skull may become nodular and it may attain a depth of more than a centimetre. This thickening consists of spongy bone containing large numbers of osteoblasts and the underlying dura is usually thickened and adherent.
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