The chondrocyte pericellular matrix: a model for hyaluronan-mediated cell-matrix interactions.

نویسندگان

  • C B Knudson
  • G A Nofal
  • L Pamintuan
  • D J Aguiar
چکیده

Masellis-Smith, A., Belch, A. R., Mant, M. J., ‘I’urley, E. A. and Pilarski, I,. M. (1996) Blood 87, I891 I899 ‘L’urley, E. A. and Torrance, J. (1984) Exp. Cell Kes. 161, 17-28 Weiss, J. M., Kenkl, A. C., Ahrens, ‘I-., Moll, J., Mai, B. €I., Denfeld, R. W., Schopf, E., Ponta, I I . , IIerrlich, P. and Simon, J. C. (1998) J. Invest. Dermatol. 111, 227-232 ‘I’eder, P. and Heldin, P. (1997) Am. J. Respir. Cell Mol. Riol. 17, 376-385 Savani, R. C., Hou, G., I,iu, P., Wang, C., Simons, I:. E., Grimm, P. C., Stern, R., Greenberg, A. 11. and Khalil, N. (1998) Am. J. Physiol., in the press ‘I’urley, E. A., Susten, A., Vandeligt, K. and Clary, C. (1991) J. Cell Biol. 112, 1041-1047 Samuel. S. K., Hurta, R. A. R., Spearman, M. iZ., 10621069 Wright, J. A, ‘I’urley, t:. A. and Greenberg, A. 11. (1993) J. Cell Biol. 123, 749-758 31 Iocono, J. A., Bisignani, G. J., Krummel, T. M. and Ehrlich, II. P. (1998) J. Surg. Res. 76, 1 1 1-1 16 32 Hall, C. I , . , Wang, C., I,ange, I,. A. and Turley, E. A. (1994) J. Cell Biol. 126, 575-588 33 Burridge, K., Fath, K., Kelly, ‘I,., Nuckolls, G. and Turner, C. (1988) Annu. Rev. Cell Biol. 4, 487-525 34 I evenberg, S., Katz, 13. %., Yamada, K. M. and Geiger, B. (1998) J. Cell Sci. 111, 347-357 35 I,o, Y. Y., I,uo, I,., McCulloch, C. A. and Cruz, T. F. (1998) J. Biol. Chem. 273, 7059-7065 36 Hall, C. I,., I,ange, I , . )I., Prober, D. ;I., %hang, S. and Turley, I:. .I. (1996) Oncogene 13, 2213-2224 37 Noble, P. W., McKee, C. M., Cowman, M. and Shin, II. S. (1996) J. Exp. Med. 183, 2373-2378 38 Madhani, I I . I). and link, I). G. (1998) Trends Genet. 14, 15 1 155

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Hyaluronan receptor-directed assembly of chondrocyte pericellular matrix

Initial assembly of extracellular matrix occurs within a zone immediately adjacent to the chondrocyte cell surface termed the cell-associated or pericellular matrix. Assembly within the pericellular matrix compartment requires specific cell-matrix interactions to occur, that are mediated via membrane receptors. The focus of this study is to elucidate the mechanisms of assembly and retention of ...

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Assembly of a chondrocyte-like pericellular matrix on non-chondrogenic cells. Role of the cell surface hyaluronan receptors in the assembly of a pericellular matrix.

In this study, we have examined the capacity of various cell types, which express cell surface hyaluronan receptors, to organize a chondrocyte-like pericellular matrix when given chondrocyte-derived extracellular matrix macromolecules exogenously. The assembly of a pericellular matrix was visualized by a particle exclusion assay. Without the addition of exogenous macromolecular components, none...

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Superficial zone chondrocytes from bovine articular cartilage respond predominately to HA oligosaccharides

INTRODUCTION: Articular chondrocytes exhibit an extensive hyaluronan (HA) and proteoglycan-rich pericellular matrix that is tethered to the cell surface via interactions with the HA receptor, CD44. One hallmark of osteoarthritic cartilage is the loss of proteoglycan from the extracellular matrix. This may represents the disruption of proteoglycan/HA-chondrocyte interactions. One of our experime...

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Hyaluronan in the pericellular coat: an additional layer of complexity in early cell adhesion events{

Cell adhesion is a multistage process whereby specific surface receptors interact with the corresponding ligands on the extracellular matrix or on neighboring cells. These complex interactions involve a wide variety of cellular molecules including transmembrane and cytoskeletal components, scaffolding proteins, and a wide variety of signaling enzymes. In this article we discuss recent data char...

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Hyaluronan Receptor-directed Assembly of Chondrocyte Pericellular Matrix

Initial assembly of extracellular matrix occurs within a zone immediately adjacent to the chondrocyte cell surface termed the cell-associated or periceUular matrix. Assembly within the periceUular matrix compartment requires specific cell-matrix interactions to occur, that are mediated via membrane receptors. The focus of this study is to elucidate the mechanisms of assembly and retention of th...

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Dynamic study of the transition from hyaluronan- to integrin-mediated adhesion in chondrocytes.

Membrane-bound hyaluronan mediates the initial adhesive interactions between many cell types and external surfaces. In RCJ-P chondrocytes, such early contacts are mediated through a thick hyaluronidase-sensitive coat. The early adhesion is followed by integrin-mediated interactions and the formation of stable focal adhesions. During this process, the distance between the cell membrane and the s...

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عنوان ژورنال:
  • Biochemical Society transactions

دوره 27 2  شماره 

صفحات  -

تاریخ انتشار 1999