Squalene emulsions for parenteral vaccine and drug delivery.
نویسنده
چکیده
Squalene is a linear triterpene that is extensively utilized as a principal component of parenteral emulsions for drug and vaccine delivery. In this review, the chemical structure and sources of squalene are presented. Moreover, the physicochemical and biological properties of squalene-containing emulsions are evaluated in the context of parenteral formulations. Historical and current parenteral emulsion products containing squalene or squalane are discussed. The safety of squalene-based products is also addressed. Finally, analytical techniques for characterization of squalene emulsions are examined.
منابع مشابه
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ورودعنوان ژورنال:
- Molecules
دوره 14 9 شماره
صفحات -
تاریخ انتشار 2009