[Leishmania braziliensis: report of a pediatric imported case with response to liposomal amphotericin B].
نویسندگان
چکیده
Leishmania braziliensis is the main etiologic agent of leishmaniasis in South America. A 9-year-old boy consulted for the presence of round, ulcerative lesions with raised borders that were painful and have appeared after a travel to Bolivia and Brazil. The culture for parasites showed leishmanias and the PCR was positive for L. braziliensis. The patient underwent treatment with itraconazol but due to the persistence of lesions he received liposomal amphotericin B with complete resolution of the lesions. In all lesions by L. braziliensis the treatment must be systemic due to the risk of mucosal dissemination. Liposomal amphotericin B is a convenient alternative to pentavalent antimonials given its efficacy and good tolerance.
منابع مشابه
Old world Leishmania infantum cutaneous leishmaniasis unresponsive to liposomal amphotericin B treated with topical imiquimod.
We present a case of a child with Leishmania infantum cutaneous leishmaniasis unresponsive to 2 courses of intravenous liposomal amphotericin B, a treatment failure that has not been reported in this Leishmania species. The patient responded to topical imiquimod and had no relapse. We review the literature on the treatment failure of liposomal amphotericin B for cutaneous leishmaniasis.
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Leishmania parasites cause a broad range of disease, with cutaneous afflictions being, by far, the most prevalent. Variations in disease severity and symptomatic spectrum are mostly associated to parasite species. One risk factor for the severity and emergence of leishmaniasis is immunosuppression, usually arising by coinfection of the patient with human immunodeficiency virus (HIV). Interestin...
متن کاملCase report: Severe cutaneous leishmaniasis in a human immunodeficiency virus patient coinfected with Leishmania braziliensis and its endosymbiotic virus
Leishmania parasites cause a broad range of disease, with cutaneous afflictions being, by far, the most prevalent. Variations in disease severity and symptomatic spectrum are mostly associated to parasite species. One risk factor for the severity and emergence of leishmaniasis is immunosuppression, usually arising by coinfection of the patient with human immunodeficiency virus (HIV). Interestin...
متن کاملOtolaryngologic Presentation of Mucosal Leishmaniasis
Mucosal leishmaniasis (ML) is an uncommon complication of a disease seen primarily in the developing world. A 31-year-old previously healthy man presented with six months of nasal congestion, throat pain, hoarseness, and intermittent dysphagia and odynophagia. The leishmania culture was positive, and PCR testing was consistent with Leishmania braziliensis infection. He was treated with liposoma...
متن کاملSevere Cutaneous Leishmaniasis in a Human Immunodeficiency Virus Patient Coinfected with Leishmania braziliensis and Its Endosymbiotic Virus
Leishmania parasites cause a broad range of disease, with cutaneous afflictions being, by far, the most prevalent. Variations in disease severity and symptomatic spectrum are mostly associated to parasite species. One risk factor for the severity and emergence of leishmaniasis is immunosuppression, usually arising by coinfection of the patient with human immunodeficiency virus (HIV). Interestin...
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ورودعنوان ژورنال:
- Actas dermo-sifiliograficas
دوره 98 1 شماره
صفحات -
تاریخ انتشار 2007