Effects of ethanol on Drosophila locomotion
نویسندگان
چکیده
Introduction Drugs of abuse have well-studied effects on locomotion in mammals. In general, low doses stimulate locomotion, whereas higher doses induce repetitive movements called ‘stereotypies’ and/or sedation. Repeated drug administration can lead to the development of behavioral sensitization, which is manifested as an increased response to the drug, or tolerance, which is characterized by a diminished response. Both the stimulant effects of drugs and their ability to induce behavioral sensitization have been proposed to model the positively reinforcing or rewarding properties of the drug [1,2].
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