Management of invasive fungal infections in neutropenic patients.

Invasive fungal infections (IFIs) are a well known, lifethreatening complication of neutropenia in haematologic patients. However, IFIs also affect various types of non-neutropenic patients, particularly those admitted in the hospital in critical conditions [1]. Candida spp. infections are mainly documented in intensive care units (ICUs), especially in patients undergone to major surgery, receiving broad spectrum antibiotic therapy and having a long ICU stay. Invasive Aspergillosis have been reported in pts treated with steroid therapy due to chronic obstructive pulmonary disorders with severe respiratory failure, in pts with severe liver failure, in solid organ transplant pts and a few cases have been also documented as a complication of H1N1 influenza virus infection. The population of patients admitted in ICUs is extremely heterogeneous in terms of age and degree of risk of infection. The range goes from otherwise young and healthy multiple trauma patients to heavily immunocompromised patients. Management of invasive fungal infections in non-neutropenic patients