Triplex-pumping CD-like microfluidic platform with parabolic microchannels

In this research, we propose a triplex-pumping CD-like multi-channel electrophoresis-based biomedical separation system that is driven by the interactions of the centrifugal force, the electric field force, and the Coriolis force. In this novel platform,the heat-conduction theory is implemented to formulate the relations between the sample velocity and the dimensions of the microchannel. The parabola microchannel that has the least friction force under triplex-pumping forces is determined by computer simulations. The centrifugal force control of this system is realized by the angular velocity of a DC servo motor, while the electric field is governed through multi-stage potential circuits, which are suitably designed and fabricated by sputtering using the metal mask method, and can be adjusted to provide multi-stage voltages. Experimental results demonstrated that the proposed parabola microchannels can effectively eliminate the effects of friction force.