MicrorNAs and their roles in wound repair and regeneration

نویسندگان

  • Stuart J Mills
  • Allison J Cowin
چکیده

*Corresponding author iNTroDuCTioN It was originally estimated that there were between 35,000 and 120,000 encoding genes within the DNA; however, studies revised this number down to 20,000–25,000 and it was suggested that a high level of control exists to regulate gene expression in this lower than expected number of genes1. Non-coding RNAs, in particular microRNAs (miRNAs), have been proposed as one mechanism for regulating gene expression1-3. Approximately 1000 miRNAs exist in human cells, which regulate around 30% of the genes2. MiRNAs are a novel class of endogenous, single-stranded RNAs, MicrorNAs and their roles in wound repair and regeneration

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تاریخ انتشار 2013